Abstract
Objective Atypical antipsychotics have been reported to cause significant weight gain. This study examined potential weight gain associated with the use of olanzapine or risperidone. Design A retrospective chart review. Setting Three long-term care facilities. Participants Dementia patients (n = 50) given olanzapine or risperidone for the management of noncognitive behavioral disturbances. Measurements Weight changes over a 4-month period. Results Overall, patients in both groups lost weight over a 4-month period. Four (16%) of the risperidone patients and no olanzapine patients gained more than 5 pounds. Conclusion Weight change does not seem to be a significant clinical issue for older dementia patients taking low doses of atypical neuroleptics Atypical antipsychotics have been reported to cause significant weight gain. This study examined potential weight gain associated with the use of olanzapine or risperidone. A retrospective chart review. Three long-term care facilities. Dementia patients (n = 50) given olanzapine or risperidone for the management of noncognitive behavioral disturbances. Weight changes over a 4-month period. Overall, patients in both groups lost weight over a 4-month period. Four (16%) of the risperidone patients and no olanzapine patients gained more than 5 pounds. Weight change does not seem to be a significant clinical issue for older dementia patients taking low doses of atypical neuroleptics
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