Abstract

Chemical peeling using trichloroacetic acid (TCA) is frequently used in the field of aesthetic dermatology. It is important to formulate the peeling solution properly. Standardization in the preparation of the TCA solutions is proposed with formulas that allow physicians to compare different protocols published in the medical literature. The different protocols used to prepare the TCA solutions are analyzed to determine which of the protocols are the best in practice, and conversions between these different protocols are then proposed. Variation is observed in the relative concentrations of TCA of the different solutions, and standardization is necessary to avoid mishap. The weight-to-weight TCA peel solution gives an idea about the exact mass of TCA applied on the skin, which should be a standard procedure.

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