Abstract

To explore the weight change over time and its associated factors in women from semi‐rural area in Mexico.MethodsWomen participating in a randomized controlled micronutrient supplementation trial during pregnancy in 1998 were followed in 2005 and 2008. Information on weight, physical activity (PA) and socio‐demographic information was collected on each contact (n= 632). Furthermore, in a subsample (n=100) we collected blood samples in order to explore the distribution of SNP LEPTINA 3UTR, and SNP PPARG Pro12Ala. General estimating equations (GEE) were estimated to explore the association of weight change over time, and socio‐demographic, characteristics and changes in PA level.ResultsWomen were on average 23.6±5.5y and had a parity of 2.4±1.4 when were first recruited. The combined prevalence of overweight and obesity increased from38.1% in 1997 to 74.2% and 83.6 % for 2005, and 2008 respectively. The mean BMI change was 5.1±3.3 from 1998–2008. After adjusting for potential confounders, BMI change was associated to parity, (beta coefficient 1.5± 0.05, p< 0.01), and socioeconomic level, showing that women at the highest tertile had a greater increase in BMI (p<0.01).DiscussionThe overweight and obesity in this sample increased almost 46 percentage points in a 9 years period. In women from poor semi‐rural community, having a wealthier economic status and high parity might be potential risk factors for obesity

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