Weight change among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception did not influence early discontinuation.

Abstract

A recent study published in EClinicalMedicine by Mags Beksinska and colleagues reported findings from a large randomised trial conducted in four Sub-Saharan African countries to assess weight variations among users of levonorgestrel-contraceptive implant [LNG-implant], depot medroxyprogesterone acetate [DMPA] injection, both contraceptives without estrogen, and the copper-intrauterine device [Cu-IUD]. Follow up was from baseline to 18 months after initiation of use. The results evidenced that DMPA injection and LNG-implant users gained 3.5 and 2.4 kg, respectively, compared to 1.5 kg among Cu-IUD users [1].