Wegeners Granulomatosis presenting as a small saft palate mass

Anindita Datta,Partha Pratim Das,Pran Gopal Datta

doi:10.3329/bjo.v18i1.10423

Abstract

Wegeners granulomatosis (WG) is a form of vasculitis involves small and medium-sized blood vessels. It commonly involves the upper and lower respiratory tract. However, multisystemic involvement and involvement of kidneys are possible and may lead to a life threatening condition. Therefore early diagnosis is important. Timely beginning of clinical management may considerably influence the further course of disease. Although, it may present as oro-pharyngeal mass surgical procedure is not indicated method of treatment of Wegeners granulomatosis, because it can increase the pathologic process. Here we report a case of Wegeners granulomatosis (WG) presenting as a tissue growth over the soft palate. DOI: http://dx.doi.org/10.3329/bjo.v18i1.10423Bangladesh J Otorhinolaryngol 2012; 18(1): 74-76

Highlights

Wagener’s granulomatosis (WG) is a small— and middle--vessels vasculitis
We describe a case of a 35-year-old man with symptoms of a mass in the soft palate who subsequently diagnosed Wagener’s granulomatosis on the basis of histopathology
Wegener’s granulomatosis (WG) is classified as ANCA positive vasculitis, mostly localized on the small and mediumsized blood vessels

Summary

Introduction

Wagener’s granulomatosis (WG) is a small— and middle--vessels vasculitis. The pathomorphological diagnostic criteria is known as Wagener’s triad: 1) necrotizing granlomatous inflammation of upper and/or lower respiratory tract, 2) systemic or focal necrotizing vasculitis involving arteries and vein, and 3) focal segmental necrotizing crescentic gromerulonephritis[1, 2]. We describe a case of a 35-year-old man with symptoms of a mass in the soft palate who subsequently diagnosed Wagener’s granulomatosis on the basis of histopathology. A 35-year-old man presented for consultation at Green Life Medical College Hospital, Dhaka, with pain in the throat and difficulty in swallowing for 15 days. The gums and remainder of the oral cavity were normal in appearance. Address of Correspondence: Dr Partha Pratim Das, Assistant Professor of Medicine, Dhaka Medical College, Dhaka, Bangladesh. The disease is clinically localized in oral cavity. It is a limited form of WG rather than severe one. Patient may need disease modifying drugs like Cyclophosphamide or Azathioprine on the basis of disease progression and systemic involvement in subsequent follow up

Findings

Discussion

Conclusion