Abstract
Granulomatosis with poliangeitis (Wegener) is a necrotizing granulomatous vasculitis characterized by damage in the respiratory tract, kidney, skin, nervous system ... The onset of the disease is usually indolent, with nonspecific symptoms. The most frequent initial clinical presentation is the upper respiratory tract involvement (90%). The presence of pulmonary infiltrates is 70% and bilateral and cavitary nodules in about 60%.
Highlights
Granulomatosis with poliangeitis (Wegener) is a necrotizing granulomatous vasculitis characterized by damage in the respiratory tract, kidney, skin, nervous system
In our series the average age was of 48.4 ± 20.3 years, comprising 15 men and 8 women
Initial treatment was in 21.7% only prednisone, prednisone in 65.2% with cyclophosphamide, in 4.3% was added azathioprine and in 8.7% required Rituximab for severe pulmonary involvement
Summary
Wegener granulomatosis: type of presentation and initial treatment in a series of 23 cases. Rosalia Martínez-Pérez*, Mario Leon, Julia Uceda, S Rodriguez Montero, A Muñoz, ML Velloso, JL Marenco. From 7th European Workshop on Immune-Mediated Inflammatory Diseases Noordwijk aan Zee, the Netherlands. From 7th European Workshop on Immune-Mediated Inflammatory Diseases Noordwijk aan Zee, the Netherlands. 28-30 November 2012
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