Wednesday, September 26, 2018 7:35 AM–9:00 AM ePosters: P47. Evidence from the epidemiology, process and outcomes of spine oncology (EPOSO) cohort: surgical versus radiation therapy for the treatment of cervical metastases

Abstract

BACKGROUND CONTEXT Cervical metastases have unique clinical considerations because of complex neighboring anatomy, and the unique biomechanical regions within the cervical spine. The literature regarding cervical metastases is limited to retrospective studies without comparison of different treatment regimens. PURPOSE The purpose of this study was therefore to compare surgery (+/− radiation) with radiation alone for the management of cervical metastases in a prospective manner. METHODS Patients treated with surgery and/or radiotherapy for cervical metastases between August 2013 and February 2017 were identified from the epidemiology, process and outcomes of spine oncology observational cohort. Demographic, diagnostic, treatment and health related quality of life (HRQOL) (NRS Pain, EQ-5D, SF-36v2, and SOSGOQ) measures were prospectively collected at baseline, 6 weeks, 3 months, and 6 months post-intervention. RESULTS Fifty-five patients treated for cervical metastases were identified: 38 underwent surgery (+/− radiation) and 17 received radiation alone. Surgically treated patients had higher SINS scores compared to the radiation-alone group (13.0 [SD 2.8] vs. 8.0 [SD 2.8], p CONCLUSIONS Surgically treated patients presented with significantly worse baseline pain and HRQOL scores compared to patients who underwent radiotherapy only. Preservation of pain and HRQOL was observed for patients treated with radiotherapy only compared to significant improvements for surgically treated patients.