Wearable sensing for rehabilitation after stroke: Bimanual jerk asymmetry encodes unique information about the variability of upper extremity recovery.

Abstract

Wearable sensing is a new tool for quantifying upper extremity (UE) rehabilitation after stroke. However, it is unclear whether it provides information beyond what is available through standard clinical assessments. To investigate this question, people with a chronic stroke (n=9) wore accelerometers on both wrists for 9 hours on a single day during their daily activities. We used principal components analysis (PCA) to characterize how novel kinematic measures of jerk and acceleration asymmetry, along with conventional measures of limb use asymmetry and clinical function, explained the behavioral variance of UE recovery across participants. The first PC explained 55% of the variance and described a strong correlation between standard clinical assessments and limb use asymmetry, as has been observed previously. The second PC explained a further 31% of the variance and described a strong correlation between bimanual magnitude and jerk asymmetry. Because of the nature of PCA, this second PC is mathematically orthogonal to the first and thus uncorrelated with the clinical assessments. Therefore, kinematic metrics obtainable from bimanual accelerometry, including bimanual jerk asymmetry, encoded additional information about UE recovery. One interpretation is that the first PC relates to "functional status" and the second to "movement quality". We also describe a new graphical format for presenting bimanual wrist accelerometry data that facilitates identification of asymmetries.