Abstract
Non-invasive continuous blood pressure measurement is an emerging issue that potentially can be applied to cardiovascular disease monitoring and prediction. Recently, many groups have proposed the pulse transition time (PTT) method to estimate blood pressure for long-term monitoring. However, the PTT-based methods for blood pressure estimation are limited by non-specific estimation models and require multiple calibrations. This study aims to develop a low-cost wearable piezoelectric-based system for continuous beat-to-beat blood pressure measurement. The pressure change in the radial artery was extracted by systolic and diastolic feature points in pressure pulse wave (PPW) and the pressure sensitivity of the sensor. The proposed system showed a reliable accuracy of systolic blood pressure (SBP) (mean absolute error (MAE) ± standard deviation (SD) 1.52 ± 0.30 mmHg) and diastolic blood pressure (DBP, MAE ± SD 1.83 ± 0.50), and its performance agreed with standard criteria of MAE within 5 mmHg and SD within ±8 mmHg. In conclusion, this study successfully developed a low-cost, high-accuracy piezoelectric-based system for continuous beat-to-beat SBP and DBP measurement without multiple calibrations and complex regression analysis. The system is potentially suitable for continuous, long-term blood pressure-monitoring applications.
Highlights
Blood pressure measurement is an essential technique used in cardiovascular disease monitoring.The auscultatory and oscillometric methods, which use the cuff sensor to detect systolic blood pressure (SBP) and diastolic blood pressure (DBP), are the golden benchmark and commonly used in clinical diagnosis
The piezoelectric sensor was placed on the skin above the radial artery and measured for 10 sec to obtain the continuous pressure waveform
This study developed a wearable piezoelectric-based system that uses the sum of the initial blood pressure by an oscillometric method and pressure change by a piezoelectric sensor to obtain the beat-to-beat SBP and DBP
Summary
Blood pressure measurement is an essential technique used in cardiovascular disease monitoring. The auscultatory and oscillometric methods, which use the cuff sensor to detect systolic blood pressure (SBP) and diastolic blood pressure (DBP), are the golden benchmark and commonly used in clinical diagnosis. The cuff-based technique only provides one-shot data without continuous blood pressure information and causes inconvenience due to repeated cuff inflations. A significant limitation of the cuff-based approach is the lack of continuous monitoring of adverse events for hypertensive patients. The arterial cannula is a precise method to directly measure continuous blood pressure, but the arterial cannula method uses a catheter inserted into the blood vessel that could induce potential risk by such an invasive method [1]. The non-invasive continuous blood pressure monitoring remains a significant clinical unmet need
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
