Abstract
This article introduces the general framework for the study of weak interactions in models with eight quarks. It is established that several predictions of the Kobayashi-Maskawa model remain invariant when the number of quarks increases. These are upper bounds on the mixing angles and lower bounds for the mixing of the D D and B B states. The reduced matrix elements of the box diagram are calculated for heavy quark states in the asymmetric bag model. The magnitudes of the elements are smaller than those calculated previously by alternative methods and the signs are negative. The negative signs predict that the short-lived components of these states are heavier than the long-lived ones.
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