WE‐E‐L100J‐04: Coherent Scatter Imaging for Mammography

Abstract

Purpose: To develop a new screening tool for the detection of breast cancer by the wide‐field collection of x‐ray coherent scatter from the human breast, to potentially improve the diagnosis of breast cancer. Method and Materials: Coherent scatter analysis is normally performed using a highly collimated narrow beam. This complicates adding coherent scatter analysis to screening mammography. A technique has been developed which allows broad field discrimination of coherent scatter using standard high ratio Bucky grids. Using the Kα line from a standard Mo tube, the coherent scattering angle (2θ) for normal breast tissue and cancer tissue would be 9 and 13 degrees, respectively. For the first step of work, pork and beef fat (2θ = 9 degrees) were used as a phantom for normal human breast tissue, while graphite (2θ = 12.16 degrees) was used as a phantom for breast cancer tissue. The coherent scatter images were recorded with CR plates. Tests were carried out with a 10:1 grid for a series of tilt angles and sample‐to‐grid distances. Results: The intensity distribution showed that the coherent scatter from the graphite cancer phantom where observable above the fat background at certain grid tilt angles and sample‐to‐grid distances. Theoretical calculations for the intensity distributions were compared to measurements. Conclusion: This work indicates promising potential for including coherent scatter analysis in screening mammography. The patient is not exposed to any additional x‐ray radiation. Coherent scatter is normally present but not collected. This technology provides an entirely new basis for diagnosis, which may improve the sensitivity and specificity of mammography.