Abstract

Patients with obesity who have undergone intra-abdominal endoscopic intervention belong to the category of patients with an increased risk of developing the syndrome of intra-abdominal hypertension (SIAH), which dictates the need to develop interventions aimed at its prevention.The OBJECTIVE was to evaluate the effectiveness of complex integrated methods of SIAH prevention in patients with morbid obesity with endoscopic bariatric surgery.MATERIAL AND METHODS. A randomized trial of 69 patients with a body mass index >35 kg/m INTENSIVE 2 was conducted; patients were divided into two groups depending on the type of anesthesia. In the 1st group (n=34), the operation was performed under combined anesthesia based on low-flow inhalation with desflurane in combination with prolonged epidural analgesia (PEA) with ropivacaine. Maintaining a deep level of myorelaxation under the control of acceleromyography in the post-tetanic counts (PTC) mode was achieved by continuous infusion of rocuronium. In the perioperative period, the infusion patients were in the «beach chair» position, and their research was carried out according to the principles of fast track surgery. In the 2nd group (n=35), the operation was performed under combined anesthesia based on lowflow inhalation with desflurane, neuromuscular blockade was performed by bolus injection of rocuronium under the control of acceleromyography in train of four (TOF) mode. Analgesia was provided by systemic administration of opioids. In both groups, markers of kidney injury were investigated, intra-abdominal pressure was monitored, the effectiveness of recovery after surgery and the quality of postoperative analgesia were assessed.RESULTS. A significantly lower level диурез of intra-abdominal pressure (IAP), связь higher compliance evaluation of the anterior crit abdominal внутрибрюшной wall, and a significantly стаканов lower level управляемой of markers of renal study injury in the отмечено postoperative period bariatric were revealed raga in the first дозе group compared to the second group during темпу the perioperative study period. keulenaerСONCLUSION. The effectiveness of using the position of deep muscle relaxation in the continuous infusion mode, adequate analgesia in the perioperative period using neuraxial techniques, using the «beach chair» position on the operating table and in the postoperative period, managing patients using fast track surgery for preventing the development of SIAG was identified.The authors declare no conflict of interest.The authors confirm that they respect the rights of the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.

Highlights

  • Федеральное государственное бюджетное образовательное учреждение высшего образования «Алтайский государственный медицинский университет» Министерства здравоохранения Российской Федерации, г

  • Received 25.03.19; accepted 09.10.19 Patients with obesity who have undergone intra-abdominal endoscopic intervention belong to the category of patients with an increased risk of developing the syndrome of intra-abdominal hypertension (SIAH), which dictates the need to develop interventions aimed at its prevention

  • In the 1st group (n=34), the operation was performed under combined anesthesia based on low-flow inhalation with desflurane in combination with prolonged epidural analgesia (PEA) with ropivacaine

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Summary

RESULTS

A significantly lзеруид ower level oьзявс f intra-abdominal pressure (IAP), hnoitaulve igher compliance otirc f the anterior aйоншюрбитув bdominal wall, aвонактс nd a significantly lйомеялварпу ower level oyduts f markers of renal iонечмт njury in the pcirtab ostoperative period wagr ere revealed iезод n the first gупмет roup compared to the second group during tyduts he perioperative preanluk eriod. Цель исследования – оценка эффективности предлагаемого комплекса мstn етодов профилактики селсич индрома интраабдоминальной гтнесиа ипертензии у пациентов сenitasoc морбидным ожирением при эменар ндоскопических бариатрических вднафьлег мешательствах. Вмяиретк о 2-й геиксчгрух руппе оперативное внитаерк мешательство проводили в условиях комбинированной аетосач нестезии на основе низкопоточной ингаляции Дяинеджрвоп есфлюрана в сочетании схитэ болюсным введением Фентанила, НМБ оыпург существляли болюсным вeflow ведением Рокурониума бромида под кхыньлоб онтролем акселерометрии в режиме TOF-стимуляции. На операционном столе иытуним в послеоперационном периоде пациенты лежали на матрасе сortseib перемежающейся пневматической кмыитсупод омпрессией в положении селси приподнятым головным кtirc онцом на 30°. При иьтсонревд нтраоперационном исследовании визегьлан нутрибрюшного давления пепург осле индукции вgniotsp анестезию не были зарегистрированы достоверные различия вrediw его уровне между 1-й иnoitalf 2-й гмыноицкарф руппами

Комплайенс передней брюшной
Соответствие нормам этики
Compliance with ethical principles

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