Abstract

Nobody knows what will be in future during COVID-19 delta surge and appearance of new Mu variant of COVID-19. But, everyone hopes the pandemic will end soon. The recent and current rising trend in cases and deaths not only in Southeast Asia region but also around the world warns that any travel restriction must be necessary to conduct.If people gain some immunity through either vaccination or infection, it will change into endemic stage. Unfortunately, vaccination coverage is not so high compared with world population. Thus, local people living in developing countries face the COVID-19 delta surge by fighting against with only naïve immune system. SARS-CoV-2, which is responsible for COVID-19 infection, is a novel emerging contagious agent that has found a way into human civilization. Generally, emerging and reemerging of viral infections belong to the RNA family of viruses since these viruses have high mutation rates that allow their eminent environmental adaptation with rapid evolution.Up to date,little knowledge is available about SARS-Co V-2 (1,2).

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