Abstract

The low solubility of nanocarbon materials (fullerenes, CNTs and graphene) has restricted their widespread commercial use. Functionalization, however, helps overcome this major limitation. Much work has been documented recently on water soluble fullerenes (FWS) in treating cancer (e.g. breast cancer), tumours, arthritis, Parkinson’s, influenzas and HIV-AIDS. Even an aqueous nasal spray to combat Alzheimer’s has been advocated. A recent US patent shows that FWS, based on its anti-oxidant activity, is a powerful Radical Oxygen Scavenger. FWS have been used in X-ray imaging, as MRI Contrast Agents (MRI-CA), to make solar cells and could help produce nanodevices and biosensors. This review examines this emerging field.

Highlights

  • Nanocarbon materials (NCMs) include fullerenes, carbon nanotubes and graphene, which have been recognized by the award of Nobel prizes in 1996 and 2010

  • A recent patent documents their use as antioxidants, as these are Radical Oxygen Scavengers (ROS), which are expected to serve as good theranostic platforms

  • It is known that fullerene shows little toxicity in its functionalized form. This is in spite of the possible cytotoxicity arising from the efficient generation of singlet oxygen Fullerenes are powerful antioxidants due to their ROS activity [1] and can serve as multifunctional Theranostics platforms“demonstrating the beauty and power on nanotechnology”

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Summary

Patel MK and Eswaran SV*

Regional Centre for Biotechnology, NCR Biotech Science Cluster, India Submission: April 03, 2017; Published: April 26, 2017 *Corresponding author: Eswaran SV, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad 121001, India, E-mail: Dedicated to: the memory of my father, late Mr V.

Introduction
Synthesis and characterization of nanocarbon derivatives
Water soluble fullerenes for medical applications
SWCNTs and Graphene
Application to Materials Science
Fullerene Based Sensors
Full Text
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