Water soluble (η 6-arene) ruthenium(II) complexes incorporating marine derived bioligand: Synthesis, spectral and structural studies

Abstract

A series of water soluble compounds of general formula [{(η 6-arene)Ru(HMP)Cl}], [η 6-arene = η 6-cymene ( 1), η 6-HMB ( 2), η 6-C 6H 6 ( 3); HMP = 5-hydroxy-2-(hydroxymethyl)-4-pyrone] have been prepared by the reaction of [{(η 6-arene) RuCl 2} 2] with HMP. The complexes 1 and 2 react with NaN 3 to give in excellent yield tetra-azido complexes [{(η 6-arene)Ru(μN 3)N 3} 2] (arene = cymene 4, HMB = 5) but similar reaction of complex 3 with NaN 3 yielded di-azdo complex [{(η 6-C 6H 6)Ru(μN 3)Cl} 2] ( 6). Reaction of [{(η 6-arene)Ru(μN 3)Cl} 2] with HMP in the presence of NaOMe resulted in the formation of azido complex [{(η 6-arene)Ru(HMP)N 3}]. Mono and dinuclear complexes [{(η 6-arene)Ru(HMP)(L 1)}] + and [{(η 6-arene)Ru(HMP)} 2(μL 2)] 2+ were also prepared by the reaction of complexes 1 and 2 with the appropriate ligand, L 1 or L 2 in the presence of AgBF 4 (L 1 = PyCN, DMAP; L 2 = 4,4′-bipy, pyrazine). The complexes are characterized on the basis of spectroscopic data and molecular structures of three representative compounds have been determined by single crystal X-ray diffraction study.