Water Dispersed Aspartame @Graphene Oxide Nanosensor for Electrochemical Oxidation and Sensing of Atenolol

Abstract

In present work, aspartame as an inexpensive, biocompatible and ecofriendly material have been used to modify graphene oxide via non-covalent p–p stacking in aqueous solution. The aromatic aspartame, an amphilic dipeptide derivative, as an efficient dispersing agent produces stable graphene oxide suspension through ultra-sonication. Aspartame@graphene oxide modified glassy carbon electrode was used as a nanosensor for determination of Atenololthrough cyclic voltammetry over a wide pH, scan rate and concentration range. The aspartame@ GO nanosensor detects the atenolol (b –blocker drug) to micro molar level in aqueous solution at optimized conditions. The proposed sensor can be used for detection of other biochemicals and biomolecules with high sensitivity and selectivity.