Abstract
Specific features of water and salt metabolism during space flights of varying duration are considered in the present article. Experiments involving Russian and foreign cosmonauts/astronauts were performed in order to assess the metabolism of water and minerals, renal function, and the hormonal regulation of these processes during space flights. These in-flight experiments combined with model studies contributed to the understanding of the mechanisms of osmotic and volumetric regulation in microgravity and provided the foundations for developing prophylactic and correction procedures preventing adverse changes associated with the adaptation of the human body to the extraordinary conditions of space flight.
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