Abstract

What is responsible antibiotic use? A search for a multi-stakeholder definition, quality indicators, barriers and facilitators Antibiotic resistance leads to infections that are increasingly difficult to treat. Resistance can be partially curbed through responsible antibiotic use. In this thesis, responsible antibiotic use was explored by consulting different stakeholders: antibiotic prescribers, patients, public health organisations, manufacturers and regulators. Key results: Consensus on a definition and indicators for responsible antibiotic use: these can be applied by healthcare facilities for education and to improve their antibiotic use. Experiences of hospital patients with antibiotic use and their views on responsible antibiotic use: these can be utilized to improve the communication between healthcare professionals and patients. An inventory of barriers and facilitators for responsible antibiotic use: these can be utilized to guide multisectoral antibiotic policies. These results contribute to the body of knowledge regarding the complexity of using antibiotics responsibly. They are embedded in a context of increasing awareness of the societal implications of antibiotic resistance and of the need for multisectoral actions to address the issue.

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