Abstract

Volume 1 | Issue 1 Warfarin-Induced Tissue Necrosis (WITN): Case Report and Literature Review, A Proposed Name Change Simman R*1, Gould N2 and Jackson SE3 1Plastic and Reconstructive Surgery, Pharmacology and Toxicology, Wright State University Boonshoft School of Medicine, Dayton Ohio 2Family Medicine Program, Grand View Hospital, Kettering Health Network. Dayton, Ohio 3Clinical Assistant Professor of Internal Medicine, Wright State University Boonshoft School of Medicine, Dayton, Ohio *Corresponding author: Simman R, Department of Surgery, Wright State University Boonshoft School of Medicine, E-mail: plasticsimman@yahoo.com Case Report Open Access Volume 1 | Issue 1 Journal of Surgery and Operative Care

Highlights

  • Warfarin is a commonly prescribed medication worldwide, with indications for treating acute deep vein thrombosis, pulmonary emboli and prophylactically to prevent a thrombotic event associated with atrial fibrillation and cardiac valve replacement. [1] while bleeding is the most common and serious side-effect of this medication [1], warfarin induced tissue necrosis (WITN) is a rare complication encountered

  • Its indications range from treatment of deep venous thrombosis and pulmonary emboli to the prophylaxis and treatment of thromboembolic conditions associated with atrial fibrillation and cardiac valve replacement

  • Warfarin is a commonly prescribed medication worldwide, with indications for treating acute deep vein thrombosis, pulmonary emboli and prophylactically to prevent a thrombotic event associated with atrial fibrillation and cardiac valve replacement. [1] while bleeding is the most common and serious side-effect of this medication [1], WITN is a rare complication encountered

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Summary

Introduction

Warfarin is a commonly prescribed medication worldwide, with indications for treating acute deep vein thrombosis, pulmonary emboli and prophylactically to prevent a thrombotic event associated with atrial fibrillation and cardiac valve replacement. [1] while bleeding is the most common and serious side-effect of this medication [1], WITN is a rare complication encountered. At this time, a biosynthetic collagen-based extracellular matrix, derived from porcine small intestine submucosa, was applied to areas with exposed tendons and bone, in order to promote granulation tissue and prepare the wound bed for autologous skin grafting. A biosynthetic collagen-based extracellular matrix, derived from porcine small intestine submucosa, was applied to areas with exposed tendons and bone, in order to promote granulation tissue and prepare the wound bed for autologous skin grafting Three weeks later, he required another debridement of the left foot dorsum, Annex Publishers | www.annexpublishers.com. Journal of Surgery and Operative Care a meshed split thickness skin graft was taken from the right lateral thigh and was applied to all area of the lower extremities that had good granulation tissue including the right lateral leg and the dorsum of left foot (Figure 6). The usage of advance wound care technology, and the application of skin grafts, the patients’ lower extremities heel and amputation of the extensively damaged lower legs and feet was avoided (Figures 7, 8, 9, 10, 11 and 12)

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