Abstract

Although it is well known that hyperinsulinemia is improved by exercise, insulin secretion volume has not been examined in detail. We investigated the effects of walking exercise on urinary C‐peptide immunoreactivity (CPR) excretion levels. Methods: In trial 1, six adult female volunteers participated in four experiments over 24 hours. The participants performed either only normal daily activities or walking programs at the speed of 6 km/h for 60 or 120 or 180 min/day. Total urine samples for 12 hours were collected during day (8am to 8pm) and night (8pm to 8am) after the second morning (6am to 8am) urine collection. In trial 2, similar experiments were carried out and urine samples after 8am were collected every four hours until 8pm. Results: In trial 1, urinary CPR excretion levels during day were significantly lower in 120 and 180 min walking than in non‐walking experiment. Similarly in trial 2, urinary CPR excretion levels were significantly lower in 120 and 180 min walking experiment at all times between 8am and 8 pm. Urinary adrenaline, noradrenaline and free cortisol excretion levels during 4 experiments did not significantly differ. In both trials, further effects of 180 min walking on urinary CPR excretion levels were not obtained. Conclusions: Walking at 6 km/h for more than 2 hours decreases urinary CPR excretion levels without increasing physical stress.Grant Funding Source: a grant from Kanto Gakuin University

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