Abstract

Waking up to the alarm: sleep, clocks, and making memory (s)tick.

Highlights

  • In the immortal words of Woody Allen, “time is nature’s way of keeping everything from happening at once.” There is a time to work, a time to learn, and a time to rest

  • Two original research articles harnessed the power of invertebrate model systems to reveal timeof-day effects on memory formation

  • The authors show that these time-of-day dependent differences in memory performance are associated with changes in specific activation states of the protein dCreb2, a transcription factor implicated in sleep, circadian rhythms, and memory formation

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Summary

Introduction

In the immortal words of Woody Allen, “time is nature’s way of keeping everything from happening at once.” There is a time to work, a time to learn, and a time to rest. Sleep and circadian rhythms influence brain plasticity-related processes, including neural excitability, synaptic efficacy, and cognitive abilities, such as learning and memory. This Research Topic highlights current research and views on sleep and chronobiological features of plasticity and memory in multiple species, models, and systems.

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