Abstract
(esophageal aperistalsis and hypotonic LES). Nine patients (60%) had endoscopic esophagitis, whereas all fifteen showed gastroesophageal reflux at the 24h pH-MII recording. Analyzing the type of reflux, 2 patients showed a pure acid reflux, five (33%) a non-acid reflux and the other eight (53%) had a mixed reflux, both acid and non acid. Regarding lung involvement, images of interstitial pneumonia were detected in 6 out 15 (40%). The proximal extent of liquid refluxate into the esophagus was documented in three patients, all of them with interstitial pneumonia (p>0.05 by Fisher's exact test) Conclusions: the majority of SSc patients showed both acid and non acid GERD, and these findings might help for better tailoring medical treatment. Patients with proximal extent of liquid refluxate seem to be at risk of pulmonary involvement. These preliminary data need to be confirmed in a larger cohort of SSc patients.
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