Abstract
bubbles. The sizes of the RFA-induced areas were not significantly different between the single-step and multi-step methods. [Conclusions] The present results demonstrate that increased intrahepatic pressure causes microbubbles, thus suggesting that some risk of dissemination due to RFA exists. Therefore, RFA should be performed while adjusting intrahepatic pressure to avoid generating microbubbles. From this perspective, the multistep LeVeen method is suitable for treatment.
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