Abstract

and five negatives when the bridge ELISA assay was used. The three patients who were positive for HACA in the homogenous assay also had low levels of IFX in their serum. Conclusions: A novel non-radiolabeled liquid-phase homogeneous assay with high sensitivity, accuracy and reproducibility has been developed to measure the IFX and HACA levels in serum from patients treated with IFX. This automated assay provides an important tool for clinicians to monitor and relate the clinical status of patients with their HACA and drug levels at any time during the course of treatment.

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