W1145 Small Bowel Tumors – A Not so Rare Diagnosis

Abstract

compared, change of risk group occurred in 60 gastric GISTs and numbers were group A (very low risk: 15.1% vs 76.7%), group B (low risk: 61.6% vs 13.7%), group C (moderate risk: 9.2% vs 8.2%), and group D (high risk: 4.1% vs 1.4%). There was no change of risk group in small bowel GISTs and proportions were 0%, 37.1%, 22.2%, and 40.7% in group A, B, C, and D respectively. Recurrence after complete resection occurred in 6 cases after mean follow-up period of 30.6 months. Three gastric GISTs (2/6 group C, 1/1 group D) and three small bowel GISTs (1/6 group C, 2/11 group D) metastasized. They belonged to same risk group by both grading systems. When C and D group were compared with A and B group, presence of symptom, ischemic necrosis and mucosal invasion and high cellularity showed significant statistical difference (p <0.05). Conclusions: Larger proportion of gastric GISTs showed relatively lower risk of aggressive behavior than small bowel GISTs. But high recurrence rate was noted in both gastric and small bowel GISTs of higher risk group. Presence of symptom, ischemic necrosis and mucosal invasion and high cellularity are the factors related with higher risk of aggressive behavior.