Vulnerable atheromatous plaque stabilization using extracorporeal shock wave- mediated sonoporation therapy- assisted HDL and atorvastatin combination therapy

Abstract

Background and Aims : Large mature or immature lipid core (atheroma) within a thin- fibrous cap, is called vulnerable atheromatous plaque. The management of vulnerable atheromatous plaque reduces the risk of ischemic disease and its related deaths. In this study, we developed an experimental electrohydraulic shock wave generator (0–20 kv) and investigated its effectiveness on vulnerable atheromatous plaque stabilization in the golden Syrian hamster common carotid artery.