Abstract
The UNAIDS Ethical Considerations in HIV Preventive Vaccine Research guidance document transposes to the field of clinical research on the HIV/AIDS vaccine the most recent ethical thinking on research with human beings particularly that prompted by the process of review of the Declaration of Helsinki. The document sets out to be an ethical and political guide on issues where moral mediation is difficult such as the use of placebos the inclusion of women of reproductive age and children in clinical trials or even on the world distribution of the risks inherent in clinical research. In this brief commentary I shall centre my remarks on Guidance Points 6 7 and 8 of the document as these bear most directly on the issues of social inequality and vulnerability. (excerpt)
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