Abstract

Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.

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