Abstract

The COVID-19 pandemic has spread worldwide since the first cases described in Wuhan, China in December 2019. First data on SARS-CoV2 and pregnancy included small case series with a non-quantifiable risk of materno-fetal adverse outcomes. Moreover, the question of vertical transmission of the virus is still not resolved. Large cohorts are required to allow accurate risk estimates. Our aim is to collect international data on COVID-19 and pregnancies, to present an accurate analysis of the maternal, fetal and neonatal risks in case of SARS-CoV2 infection. We created a global network in order to collect worldwide data on SARS-CoV2 infection during pregnancy. Any pregnant women with a suspected or confirmed SARS-CoV2 infection is eligible. A REDCAP secure web platform was developed to give access to a turnkey tool to collect data. Sociodemographic, medical history and baseline characteristics of the patient are collected at enrollment, as well as exposure information. Maternal, fetal and neonatal monitoring and outcomes are collected in a follow-up form. Our network includes 198 centres in 23 countries. As of 12 May 2020, we have collected data about 261 patients. The COVI-PREG initiative aims to bring to international researchers a friendly-user platform to collect similar data worldwide. This partnership will allow researchers and healthcare professionals to better characterise the disease course and spectrum, to estimate associated risks and to identify specific risk factors that could be used to define screening strategies in pregnant women and adequate monitoring of their pregnancies. Supporting information can be found in the online version of this abstract Supporting Information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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