VP27.08: Reliability of corpus callosum‐fastigium and tectal length measurements in the third trimester

Abstract

To examine the reliability of corpus callosum-fastigium length (CCF) and tectal length (TL) measurements for the evaluation of fetal midbrain in the third trimester of gestation. A prospective cohort of 33 singleton low-risk pregnancies were enrolled for fetal neurosonography assessment. Neurosonography was performed between 31.6 and 32.2 weeks of gestation. Two blinded-observers measured off-line CCF and TL twice using preselected 2D images of mid-sagittal cranial plane. Intra- and interobserver agreements for CCF and TL were evaluated by using the intraclass correlation coefficient (ICC) and Bland-Altman plots. The mean values obtained were 44.44 ± 0.72mm for CCF and 10.21 ± 0.13mm for TL. The mean interobserver difference was -0.0292 ± 0.3984 for CCF (P = 0.676) and 0.0758 ± 0.2822 for TL (P = 0.133). The ICCs for interobserver and intraobserver analysis showed excellent agreement for both CCF and TL. CCF intraobserver: 0.987 (95% CI, 0.974–0.995), interobserver: 0.964 (95% CI, 0.927–0.982) and TL intraobserver: 0.967 (95% CI, 0.933–0.986) and interobserver: 0.963 ( 95% CI,0.895–0.984). Figure 1 shows mid-sagittal fetal midbrain measurements. Corpus callosum-fastigium and tectal length measurements showed an excellent intraobserver and interobserver agreement. Corpus callosum-fastigium and tectal length could be used as reproducible markers of fetal midbrain assessment. Supporting information can be found in the online version of this abstract Supporting Information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.