Abstract

Background Medication errors occur frequently in intensive care units (ICU). Voluntarily reported medication errors form an easily available source of information. Objective This study aimed to characterize prescribing, monitoring and medication transfer errors that were voluntarily reported in the ICU, in order to reveal medication safety issues. Setting This retrospective data analysis study included reports of medication errors from eleven Dutch ICU's from January 2016 to December 2017. Method We used data extractions from the incident reporting systems of the participating ICU's. The reports were transferred into one database and categorized into type of error, cause, medication (groups), and patient harm. Descriptive statistics were used to calculate the proportion of medication errors and the distribution of subcategories. Based on the analysis, ICU medication safety issues were revealed. Main outcome measure The main outcome measure was the proportion of prescribing, monitoring and medication transfer error reports. Results Prescribing errors were reported most frequently (n = 233, 33%), followed by medication transfer errors (n = 85, 12%) and monitoring errors (n = 27, 4%). Other findings were: medication transfer errors frequently caused serious harm, especially the omission of home medication involving the central nervous system and proton pump inhibitors; omissions and dosing errors occurred most frequently; protocol problems caused a quarter of the medication errors; and medications needing blood level monitoring (e.g. tacrolimus, vancomycin, heparin and insulin) were frequently involved. Conclusion This analysis of voluntarily reported prescribing, monitoring and medication transfer errors warrants several improvement measures in these processes, which may help to increase medication safety in the ICU.

Highlights

  • MethodMedical errors occur frequently in intensive care units (ICU’s) [1, 2]

  • There are a few studies on voluntarily reported Medication errors (ME) in the ICU available [6, 9,10,11,12], giving insight into the specific epidemiology of ME in the ICU

  • Medication errors (ME) account for most of the medical errors in the ICU [2, 4] and seem to occur at a higher frequency and with a greater likelihood for harm in ICU patients compared to non-ICU patients [5,6,7]

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Summary

Introduction

Medical errors occur frequently in intensive care units (ICU’s) [1, 2]. This can be attributed to complex patient conditions, acute life-sustaining treatments and a considerable workload fluctuation [1,2,3,4]. Kane-Gill et al [6] found that the types of voluntarily reported ME, contributing factors, drug classes and outcomes were different in ICU’s compared to the general care units. They concluded that there is a need for ICU specific surveillance systems for ME, so that systematic improvements specific to the ICU environment can be implemented. Reported medication errors form an available source of information

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