Abstract
The partial molar volumes, isentropic compressibilities, partial molar isentropic compressions and transfer molar quantities of cyclic alanylalanine in water and in aqueous solutions of MnCl2, NiCl2 and ZnCl2 were determined using the experimental density and speed of sound values. Refractive indices of all the solutions were recorded to calculate the molar refractions. The molecular interactions existing in the systems have been discussed based on the derived parameters. It has been found that M2+-O2H bond distances of hydrated cations influence on the volumetric properties of cyclic alanylalanine. Further, the greater effect of hydrophobic hydration has been substantiated by the Sv values of least square fits of apparent molar volume against solute molality.
Highlights
The behavior of protein molecules in various environments is of vital importance to the scientific world
We report the densities, ultrasonic velocities and refractive indices of cyclic alanylalanine in water and in aqueous MnCl2, NiCl2 and ZnCl2 solutions over a wide range of composition and temperature T = (293.15 to 313.15) K
The molecular interactions of cyclic alanylalanine in water and in aqueous MnCl2, NiCl2 and ZnCl2 solutions have been analyzed in this study
Summary
The behavior of protein molecules in various environments is of vital importance to the scientific world. Cyclic dipeptides are found to be the most suited model compounds for the thermodynamic studies of protein molecules. In particular they have the properties like close packed amino-acid groups, hydrogen bonding, Van der Waals contact and absence of end groups [3]. Owing to the biological importance of transition metal ions [11,12,13,14,15], the volumetric, acoustic and refractometric study of cyclic alanylalanine in aqueous metal salt solutions can reveal some of the structural interactions taking place in such systems. The derived parameters calculated from these experimental values have been discussed in the light of various interactions taking place in the above said system
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