Abstract
BackgroundThe objective of this study was the quantification of myocardial motion from 3D tissue phase mapped (TPM) CMR. Recent work on myocardial motion quantification by TPM has been focussed on multi-slice 2D acquisitions thus excluding motion information from large regions of the left ventricle. Volumetric motion assessment appears an important next step towards the understanding of the volumetric myocardial motion and hence may further improve diagnosis and treatments in patients with myocardial motion abnormalities.MethodsVolumetric motion quantification of the complete left ventricle was performed in 12 healthy volunteers and two patients applying a black-blood 3D TPM sequence. The resulting motion field was analysed regarding motion pattern differences between apical and basal locations as well as for asynchronous motion pattern between different myocardial segments in one or more slices. Motion quantification included velocity, torsion, rotation angle and strain derived parameters.ResultsAll investigated motion quantification parameters could be calculated from the 3D-TPM data. Parameters quantifying hypokinetic or asynchronous motion demonstrated differences between motion impaired and healthy myocardium.Conclusions3D-TPM enables the gapless volumetric quantification of motion abnormalities of the left ventricle, which can be applied in future application as additional information to provide a more detailed analysis of the left ventricular function.
Highlights
The objective of this study was the quantification of myocardial motion from 3D tissue phase mapped (TPM) CMR
The objective of this study is to investigate the feasibility of application of volumetric tissue phase mapping for quantification of myocardial motion parameters based on velocity, displacement and strain data
The navigator efficiency of all volunteers and patients was between 30% and 60%, the actual acquisition duration was between 25 and 52 minutes
Summary
The objective of this study was the quantification of myocardial motion from 3D tissue phase mapped (TPM) CMR. Recent work on myocardial motion quantification by TPM has been focussed on multi-slice 2D acquisitions excluding motion information from large regions of the left ventricle. Cardiac motion quantification of the whole left ventricle with tissue phase mapping (TPM) appears important for improved understanding of the myocardial motion pattern as well as for improving diagnosis and therapy in many cardiac diseases like asynchrony or left bundle brunch block (LBBB). Without losing substantial information of the motion pattern, view sharing enables a reduction of the overall TPM image acquisition time by 37.5% [8], k-t BLAST by 50% [15] and SENSE by 75% [16]. SENSE acceleration appears as the most promising candidate for establishing a volumetric TPM data acquisition
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
