Abstract

Background: The frequency of sudden cardiac arrest (SCA) is inversely related to left ventricular (LV) function, yet many events occur in patients with an ejection fraction (EF) of >35% who are not currently candidates for implantable cardioverter-defibrillator therapy. We hypothesized that quantifying regional inhomogeneity in myocardial sympathetic innervation and/or viability (scar and hibernating myocardium) could provide an approach to identify subgroups at the highest risk of SCA.

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