Voltammetric determination of Nordiazepam at meniscus modified silver solid amalgam electrode

Abstract

Abstract New electrochemical method for determination of Nordiazepam (NDZ) at meniscus modified silver solid amalgam electrode (m-AgSAE) was developed utilizing differential pulse voltammetry (DPV). The pH effect on the current response of NDZ was studied in the mixture of Britton-Robinson buffer (BR) and methanol (9:1) with optimum pH value of 10. The calibration dependences were examined under the optimal conditions and linearity in the range from 2 × 10−6 to 1 × 10−4 mol L−1 with limit of quantification of 1.7 × 10−6 mol L−1 were accomplished.