Voltammetric and corrosion studies of the ionophoric antibiotic–salinomycin and its determination in a soil extract

Abstract

Salinomycin monosodium salt (SLM) is a widely used ionophoric antibiotic with a broad spectrum of activity. In this paper, a study is reported on the first electrochemical investigation of SLM. The use of square wave voltammetry (SWV) in combination with a renewable silver amalgam film electrode (Hg(Ag)FE) is presented for the determination of SLM in a spiked soil extract. A reduction peak at −1.40V vs. an Ag/AgCl/KCl reference electrode was obtained in Britton–Robinson (B–R) buffer (pH7.0). The influences of conditioning potential and time, frequency, amplitude, step potential and equilibration time were studied. This electroanalytical procedure was used to determine SLM on an Hg(Ag)F electrode at a concentration range of 2.5×10−7–2.5×10−6molL−1. The precision and repeatability of the method were checked. The limit of detection and quantification were 7.8×10−8molL−1 and 2.5×10−7molL−1, respectively. To understand the SLM electrode mechanism, the cyclic voltammetry (CV) technique was applied. Moreover, the effect of SLM on the corrosion properties of stainless steels used to produce metal bowls and feed troughs was studied using the potentiodynamic method.