Abstract
Fresh rat neural lobe slices were incubated in the presence of [ 125I]α-scorpion toxin (ScTX), a specific marker of Na + channels. Quantitative electron microscope autoradiography revealed preferential, irregularly spaced labeling of the axolemma of neurosecretory axons, with a significantly higher crude specific activity than any other neuronal or non-neuronal compartment. The number of specific binding sites at the neural lobe surface was calculated to be about 23 per μm 2 of axolemma.
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