Abstract

Fluorescence lifetime imaging (FLIM) was used to study the behaviour of a BODIPY dye in a giant unilamellar vesicle (GUV) in the presence of an electric field. The modulation of the electric field resulted in distinctive fluorescence lifetime changes in line with environment alterations within the membrane mimic.

Highlights

  • Voltage-induced fluorescence lifetime imaging of a BODIPY derivative in giant unilamellar vesicles as potential neuron membrane mimics†

  • The modulation of the electric field resulted in distinctive fluorescence lifetime changes in line with environment alterations within the membrane mimic

  • Fluorescence lifetime imaging microscopy (FLIM) is viewed as one of the most powerful techniques to determine the spatial distribution of excited state lifetimes in a sample together with picosecond time response

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Summary

Introduction

Voltage-induced fluorescence lifetime imaging of a BODIPY derivative in giant unilamellar vesicles as potential neuron membrane mimics†. Fluorescence lifetime imaging (FLIM) was used to study the behaviour of a BODIPY dye in a giant unilamellar vesicle (GUV) in the presence of an electric field. The modulation of the electric field resulted in distinctive fluorescence lifetime changes in line with environment alterations within the membrane mimic.

Results
Conclusion

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