Abstract
The essential target of the tumor’s treatment is how to destroy its tissues. This work is dealing with the thermal damage of the tumor tissue due to the thermoelectrical effect based on the Thomson effect. The governing equation of tumor tissue in concentric spherical space based on the thermal lagging effect is constructed and solved when the surface of the tumor tissue is subjected to a specific electric voltage. Different voltage and resistance effects have been studied and discussed for three different types of tumor tissues. The thermal damage quantity has been calculated with varying values of voltages and times. The voltage has significant effects on the temperature and the amount of the irreversible thermal damage of the tumor. Electrotherapy is a successful treatment. This work introduces a different model to doctors who work in clinical cancer to do experiments using electricity to damage the cancer cells.
Highlights
Electrochemotherapy with a low-level direct electric current (DEC) is a therapeutic approach that consists of applying a direct electric current across the tumor tissues, and it has been proved to be a sure, effective, and relatively cheap treatment of tumors [1]
In this work, governing partial differential equation of tumor tissue in concentric spherical space based on thermal lagging effect and Thomson effect is solved in the Laplace transform domain
The surface of the tumor tissue is subjected to an electric voltage
Summary
Electrochemotherapy with a low-level direct electric current (DEC) is a therapeutic approach that consists of applying a direct electric current across the tumor tissues, and it has been proved to be a sure, effective, and relatively cheap treatment of tumors [1]. The electrical properties of living tissues have been studied by many researchers to evaluate the effect of electromagnetic fields [3]. Nuccitelli discussed the use of pulsed electric fields in cancer therapy based on pulse length, millisecond domain, microsecond domain, and nanosecond domain [4]. Many authors have confirmed that the electrical properties of all types of tumors tissue (muscle, fat, breast, etc.) vary after applying electroporation pulses [5,6,7,8,9,10,11]
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