Abstract
BackgroundInternal voids of materials can serve a hub for microorganism and affect the sealing ability. This study aimed to evaluate the sealing performance of calcium silicate-based cements in immature teeth treated with regenerative endodontics.MethodsTwenty single root canals from immature permanent premolars were prepared using regenerative endodontic protocols. The root canals were randomly divided into two groups and sealed with mineral trioxide aggregate (MTA) and Biodentine (BD). The teeth were kept in humid environment for 7 days and scanned using micro-computed tomography. The voids within the cements were segmented and visualized using image processing, incorporating the modified Otsu algorithm. The porosity of each sample was also calculated as the ratio between the number of voxels of voids and the volume of the cements. Tortuosity was also calculated using the A-star algorithm.ResultsVoids larger than 70 μm were predominantly observed in the top and interfacial surface of cements. The others were evenly distributed. MTA and BD showed the same level of porosity and tortuosity at interfacial surfaces. In inner surfaces, MTA showed more less porosity and tortuosity compared to BD (p < 0.05).ConclusionsThere were no differences in sealing performance between MTA and BD.
Highlights
Internal voids of materials can serve a hub for microorganism and affect the sealing ability
The tortuosity analysis showed similar results (Table 2); with significant differences only being observed at the inner surfaces (p < 0.05)
This study evaluated the 3D void structures of mineral trioxide aggregate (MTA) and BD using micro-CT analysis, when MTA and BD are used as sealing materials in regenerative endodontic procedures (REPs)
Summary
Internal voids of materials can serve a hub for microorganism and affect the sealing ability. Anatomy of immature permanent teeth is characterized by wide root canals with open apex and thin dentinal walls. Voids at the interface between the material and the dentinal wall may serve as hubs for microorganism, leading to microleakage [6]. Coronal microleakage has been regarded as potential cause of treatment failure after endodontic treatment. A previous in vivo study demonstrated that coronal microleakage could lead to periapical inflammation [7]. These voids could be a cause of re-infection as they are in contact with potentially infected canal walls [8]. The sealing ability of the materials can be influenced by void formation
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