Abstract
Ninety-one of one hundred six patients with T 1 and T 2 vocal cord cancer involving the anterior commissure of the larynx were treated by primary irradiation. In twenty-two of the ninety-one, recurrent cancer developed; subsequent surgical therapy was offered and accepted by twenty. Eight of the ninety-one patients (8.8 per cent) are considered to have failures in that they either died of cancer, were lost to follow-up study, or died of complications of the treatment. Patients whose lesions are clinically limited to the vocal cord and the anterior commissure, with or without change of mobility of the cord, should be selected for primary radiation therapy. Patients in whom there is clinical extension of the lesion off the vocal cord in addition to involvement of the anterior commissure will usually require surgical therapy with or without radiation therapy.
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