Abstract

The implementation of novel coaxial dipole antennas has been shown to be a satisfactory diagnostic platform for the prediction of orthopaedic bone fracture healing outcomes. These techniques require mechanical deflection of implanted metallic hardware (i.e., rods and plates), which, when loaded, produce measurable changes in the resonant frequency of the adjacent antenna. Despite promising initial results, the coiled coaxial antenna design is limited by large antenna sizes and nonlinearity in the resonant frequency data. The purpose of this study was to develop two Vivaldi antennas (a.k.a., “standard” and “miniaturized”) to address these challenges. Antenna behaviors were first computationally modeled prior to prototype fabrication. In subsequent benchtop tests, metallic plate segments were displaced from the prototype antennas via precision linear actuator while measuring resultant change in resonant frequency. Close agreement was observed between computational and benchtop results, where antennas were highly sensitive to small displacements of the metallic hardware, with sensitivity decreasing nonlinearly with increasing distance. Greater sensitivity was observed for the miniaturized design for both stainless steel and titanium implants. Additionally, these data demonstrated that by taking resonant frequency data during implant displacement and then again during antenna displacement from the same sample, via linear actuators, that “antenna calibration procedures” could be used to enable a clinically relevant quantification of fracture stiffness from the raw resonant frequency data. These improvements mitigate diagnostic challenges associated with nonlinear resonant frequency response seen in previous antenna designs.

Highlights

  • Orthopaedic bone fracture healing complications remain pervasive, despite ongoing improvements to clinical standards of care

  • Future studies are recommended for evaluating the applicability of the miniaturized antenna for predicting healing induced bone fracture stiffness progression

  • These results agree with previous antenna development studies [25], which were foundational to the development of subsequent clinical diagnostic devices [26, 27]

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Summary

Introduction

Orthopaedic bone fracture healing complications remain pervasive, despite ongoing improvements to clinical standards of care. Long bone fractures, such as those of the tibia, exhibit failed healing (nonunion) in up to 12% of cases [1]. Healing outcome can be improved, and patient suffering reduced, in cases where rapid diagnosis of adverse fracture healing is achieved to advise corrective therapies during the early stages (< 30 days post-surgery) of fracture healing [3, 4]. Achieving an early prediction of healing outcome remains difficult using current clinical diagnostic tools: namely, VOLUME XX, 2017.

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