Abstract
It is worth mentioning that the high output of different physiological responses under the expression of vgb, may have a considerable effect on the enzyme productivity, dairy industry, heavy metal uptake, biodegradation of different organic pollutants and other applications. The expression of bacterial haemoglobin is useful in lessening the load of perceived toxic conditions such as high oxygen levels. This in turn probably has the same impact on some peripheral toxic materials. This, hemoglobin biotechnology can be extended to enhance production of pollutants degrading enzymes or production of some valuable manufacturing materials on the case-by-case bases. It is likely that the mechanism of bacterial hemoglobin (VHb) effects is intermediated via an oxygen trapping action. This may drive the enrichment of ATP production, which is mostly required for higher productivity of needed substances for that activity.
Highlights
Vitreoscilla sp. are strictly aerobic Gram-negative bacteria that live in oxygen-limited environments such as deep pools and cow dung (Pringsheim, 1951)
In Vitreoscilla or E. coli transformed with vgb, Vitreoscilla hemoglobin (VtHb) levels were found to be increased when the cells were grown at low oxygen concentrations (Boerman and Webster, 1982; Dikshit et al, 1990)
Further studies demonstrated that VtHb-containing E. coli cells grow more quickly and to a higher density compared with non-VtHb containing cells (Khosla et al, 1990; Khosravi et al, 1990; Joshi and Dikshit, 1994)
Summary
Vitreoscilla sp. hemoglobin (VHb) Expression in Heterologous Hosts: Some Aspects of Their Biotechnological Application. Al Tarawnehc aBiology Department, Mutah University, Mutah, Karak, 61710, Jordan; bDepartment of Medical Laboratory Sciences, Mutah University, Mutah, Karak, 61710, Jordan; cPrince Faisal Center for Dead Sea, Environmental and Energy Research, Mutah University, Karak, Jordan
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More From: Journal of Basic and Applied Research in Biomedicine
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