Abstract
Solid organ transplantation is a popular solution for many end stage organ failures. The functional evaluation of these transplanted organs is multi-factorial and involves many aspects involving organ function, overall patient wellbeing and quality of life. Literature reports on vitamin status following transplantation had been collected together in this review article. This review summarizes the current status of research in this area with focus on reported deficiencies in vitamins following solid organ transplantation. The deficiencies in either fat-soluble vitamins like vitamin D, vitamin A and vitamin K as well as water soluble vitamins like vitamin B6, vitamin B12 and thiamine have been summarized. The reported deficiencies are noteworthy and necessitate a critical evaluation and interventions in many transplantation programs
Highlights
Alterations in vitamin status following solid organ transplantation have been reported
The data within articles were extracted, information relating to vitamin status following transplantation
The full text articles that include vitamin status evaluated following transplantation were included in the review
Summary
Alterations in vitamin status following solid organ transplantation have been reported. A wide range of alteration can occur and may include both fat soluble vitamins (A, D, E and K) as well as water soluble vitamins (B1, B2, B6, niacin, B12). Vitamin status may be affected following transplantation by inadequate intake or supplementation, disturbed activation by different organ systems, or by immunosuppression. The extent and severity of vitamin level alteration varies considerably depending on the type of organ transplanted and the perioperative nutrition support supplied. Vitamin deficiencies associated with organ dysfunction are corrected once a new allograft is received. The purpose of this review is to explore clinical issues in vitamin status following solid transplantation
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