Abstract
THE existence of vitamin P was first postulated by Szent-Gyorgyi and his colleagues1,2 in 1935 and 1936. Other workers have since failed to substantiate their original conclusions3,4. However, so far as guinea pigs are concerned, Zacho5 and Bacharach6 have obtained considerable evidence that vitamin P deficiency is a reality. The fall in capillary resistance obtained by Bacharach and his co-workers6,7 is small, but they have been able to show a statistically significant difference between the capillary fragility of the normal and the P-deficient guinea pig.
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