Abstract
Vitamin D (VD) is a fat-soluble vitamin that exists in two major forms, ergocalciferol (VD2) and cholecalciferol (VD3). 1,2 The classiceffects of VD involve calcium and phosphorus homeostasis and regulation of bone mineralization. More recently, it has been recognized thatVD has a host of other intra-organ autocrine, paracrine, and intracrine actions that may result in significant immunomodulatory effects. 1 As aresult, there is greater interest in the possible role of VD defficiency in the development of chronic in ammatory conditions such as in ammatorybowel disease (IBD). 1–3 This chronic, incurable, immune-mediated in ammatory disorder of the gastrointestinal tract consists of twosubtypes, Crohn disease (CD) and ulcerative colitis. 4
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