Abstract

To the Editor: We read with interest the article by Leslie et al. (1), which revealed that poor vitamin D status correlates with lower bone mineral density and skeletal density. Many factors contribute to the increased risk of osteopenia and osteoporosis in inflammatory bowel disease (IBD), including malabsorption, systemic inflammation, medications, hormone deficiency, malnutrition, and lifestyle (2,3). Vitamin D has gained increased attention due to its relationship with calcium absorption in the small intestine and ultimately bone mineralization. It has been shown that vitamin D levels are suboptimal in many patients with osteoporosis worldwide, including those with IBD (4).

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