Vitamin D levels in Coronavirus-infected Individuals and its Correlation with Certain Hematological Markers

Abstract

The world and nearly all our health care system were confronted by a significant threat which was declared by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Determining the SARS-CoV-2 or COVID-19’s prognostic and modifiable measures surely would largely contribute to outcome improving despite the deficiency of causative therapy that affected nearly 200 million people, 3.5 million fatal incidences, and it is still airborne. The research in hand examined probable relations between the levels of vitamin D (VitD) and immunological markers. Hence, a sample of 200 lecturers and students from Cihan University-Erbil were assigned, (150 males, 50 females) whom ages were between 22 to 25, with some respondents were treated from a previous COVID-19 infection. The results showed that 98 (or 49%) of the 200 samples had Covid-19 infection. Males 60/98 had a greater prevalence rate (61%), whilst females 38/98 had a lower rate (39%). According to immunological ELISA results, every patient had positive IgG antibodies and negative IgM antibodies. Compared to the healthy group, the serum levels of IgE rose considerably in Covid-19 patients. However, when compared to the healthy group, the serum level of vitamin D3 in the Covid-19 recovered patients showed a considerable reduction. The mean results for hematological parameters indicated a non-significant increase in the number of red blood cells relative to the healthy group, but a significant increase in the WBC count, Hb concentration, and platelets. Thus, the result indicates the necessity for interventional studies on vitamin D supplementation in SARS-CoV-2 infected persons by showing a correlation between vitamin D deficit and WBC count during COVID-19 recovery.