Abstract
BackgroundThe role of vitamin D in increased mortality with SARS-COV-2 virus, namely, COVID-19, remains uncertain. We analysed all the patients who were treated as COVID-19-positive with or without a positive...
Highlights
Vitamin D has an important role in maintaining healthy teeth, bones and immunity
We aimed to investigate any relationship of vitamin D level with 30-day mortality with COVID-19
A total of 433 patients were tested for SARS-CoV-2 RNA swab test and had blood tests for evaluating vitamin D levels within last 3 months
Summary
Vitamin D has an important role in maintaining healthy teeth, bones and immunity. Sunlight remains the most important source of vitamin D in nature.[1 2] vitamin D is available in certain foods like oily fish, eggs, fortified margarines and some others, the amount of available vitamin D is not enough even with increased consumption to meet the daily vitamin D requirement. In contrast to vitamin D3, vitamin D2 is available as fortified food or given by the supplements. Both are bound to the vitamin D binding protein (VDBP) and transported to the liver and converted to 25-h ydroxyvitamin D and are commonly agreed to be the metabolite as the major storage form of vitamin D in the body. 25-Hydroxyvitamin D is converted to 24,25-dihydroxyvitamin D, which is the most abundant product of 25-h ydroxyvitamin D catabolism with half-life of approximately 7 days, with serum concentrations up to approximately 10 nmol/L.4. The role of vitamin D in increased mortality with SARS-COV-2 virus, namely, COVID-19, remains uncertain. We analysed all the patients who were treated as COVID-19-positive with or without a positive swab and were tested for vitamin D levels. Larger prospective studies will be needed to confirm these findings
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