Vitamin D Is Associated With Functional Mobility Not With Muscle And Balance In Osteoporotic Women

Abstract

PURPOSE: The aim of this study was to evaluate the different levels of vitamin D are associated with knee muscle strength, postural balance and functional mobility in women with postmenopausal osteoporosis. METHODS: This is a cross-sectional observational study, without intervention, of 63 osteoporotic elderly women. The volunteers were divided into four groups according to the vitamin D blood level. Participants then underwent the Timed Up and Go Test to measure functional mobility. The postural balance was assessed on the AccuSway Plus portable force platform. Isokinetic dynamometry was performed using the Biodex® Multi-joint System 3. Data are reported as mean ± standard deviation or 95% confidence interval (CI), and were analyzed with the subjects divided into quartiles according to their 25(OH)D level. Statistical significance was set at P<0.05. RESULTS: No significant differences between groups were observed in all demographic and clinical variables, strength, or postural balance, except for the 25(OH)D level, which showed a significant different between groups (P<0.001). However, significant differences were found in the Timed Up and Go Test: the women with the highest 25(OH)D levels (G4) showed greater performance than those with lowest 25(OH)D levels (G1) (P<0.008) (Figure 1). CONCLUSIONS: Women of G2 and G3 showed intermediate Timed Up and Go Test performances that were not statically different from both G1 and G4. Vitamin D blood level was associated with functional mobility in women with postmenopausal osteoporosis.